CEL™ is designed to act on 10 key cellular markers of aging. These include:
- Telomere protection , which preserves the DNA “caps” essential for longevity.
- Preservation of stem cells , which maintains the regenerative potential of the skin.
- Mitochondrial vitality , which improves cellular energy and repair mechanisms.
- Stimulation of autophagy , which promotes healthy renewal and recycling of damaged cells.
- The integrity of the skin barrier , which strengthens tight junctions and defense mechanisms.
- Microbiome balance , which supports the skin's natural ecosystem.
Unique. Exclusive. Patent pending.
Skin aging does not depend on a single factor, but on a chain of biological mechanisms: mitochondrial decline, chronic inflammation, microbiome imbalance, cellular senescence... So many invisible signals which, together, accelerate the age of the skin.
This is precisely where the CEL™ Complex (Cellular Epigenetic Longevity) comes in. By acting at the heart of these biological pathways, it restores the skin's natural ability to self-regulate, repair itself, and resist aggression.
CEL™ works where it all begins: in the cells.
Cells that function better = skin that ages more slowly.
+34.76% of procollagen I-producing cells in the dermis.
With age, the production of procollagen I can decrease by approximately 50%.
On 56-year-old skin tissue, a single application of the CEL™ complex was associated with a 34.76% increase in the number of dermal cells actively producing procollagen I, compared to the baseline level.
The magnitude of this response after a single application is comparable to the entire age-related decrease in procollagen I observed in scientific literature, with a production level corresponding to that found in skin aged 25 or younger.
The two studies are not methodologically identical and no direct clinical equivalence can be claimed. However, the marker studied is the same, the methodologies are similar, and both the direction and magnitude of the response converge.
The skin's natural maintenance system is reactivated.
A phenomenon documented for the first time following the application of a topical treatment.
Young, healthy skin possesses its own internal management system. It constantly evaluates cells that are functioning correctly, repairs those that can be, and eliminates those that no longer can.
With age, this system slows down. Cells that should be eliminated gradually accumulate, and the tissue becomes less capable of regulating itself.
After a single application on healthy, intact skin tissue, two markers involved in this maintenance system increased significantly over the following 4.5 hours.
The first participates in cell evaluation and repair. The second is involved in selective renewal.
To date, no other topical treatment has shown this specific profile in published scientific literature.
The conclusion of the independent anatomical pathologist: a coordinated cellular renewal response.
Tested on healthy skin. Not on previously damaged skin.
Many cosmetic tests first damage the skin, notably with UV rays, which naturally triggers its repair mechanisms, which can in turn increase procollagen production, regardless of the product being tested.
It also creates an artificially low starting level from which the skin can then recover.
A portion of the result attributed to the product may therefore stem from the skin's natural repair process.
We have chosen a more demanding test. The tissue has never been damaged.
No artificially lowered starting level. No repair reaction triggered beforehand.
And yet, in this healthy and intact skin tissue, 34.76% more cells in the dermis were actively producing procollagen I compared to the initial level.
The CEL™ complex helped recreate the conditions allowing cells that always had the capacity to do their job better.