Aging is not in our genes.

Less than 3% of aging is genetic. The remaining 97% is determined by epigenetic factors : stress, environment, lifestyle, and diet, among others. CEL™ was created to address these epigenetic changes, supporting the skin's ability to function, regenerate, and defend itself.

Target key aging mechanisms for younger, longer-looking skin.

CEL™ is designed to act on 10 key cellular markers of aging. These include:

  • Telomere protection , which preserves the DNA “caps” essential for longevity.
  • Preservation of stem cells , which maintains the regenerative potential of the skin.
  • Mitochondrial vitality , which improves cellular energy and repair mechanisms.
  • Stimulation of autophagy , which promotes healthy renewal and recycling of damaged cells.
  • The integrity of the skin barrier , which strengthens tight junctions and defense mechanisms.
  • Microbiome balance , which supports the skin's natural ecosystem.

Unique. Exclusive. Patent pending.

Skin aging does not depend on a single factor, but on a chain of biological mechanisms: mitochondrial decline, chronic inflammation, microbiome imbalance, cellular senescence... So many invisible signals which, together, accelerate the age of the skin.

This is precisely where the CEL™ Complex (Cellular Epigenetic Longevity) comes in. By acting at the heart of these biological pathways, it restores the skin's natural ability to self-regulate, repair itself, and resist aggression.

CEL™ works where it all begins: in the cells.

Cells that function better = skin that ages more slowly.

Zombie Cells vs. CEL™

Senescent cells, or “zombie cells,” are cells at the end of their life. Their presence produces inflammatory factors that damage other cells and accelerate aging.

Instead of targeting zombie cells, Skin Diligent's CEL™ actively supports cells throughout their life cycle to keep them healthy and delay senescence as much as possible. Our approach is to optimize skin cell health while they are active, without waiting for them to reach inflammatory senescence.

"The real breakthrough in skin care is formulating products from a cellular perspective. Any ambiguity can be answered scientifically if we ask ourselves what effect the product has on skin cells."


Tule Park, Co-founder of Skin Diligent & Specialist in epigenetic skin care.

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